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HUNK — PTPN11
Text-mined interactions from Literome
Sol et al., J Virol 1999
(Parvoviridae Infections) :
Since
B19- and NS-1 induced apoptosis was inhibited by caspase 3, 6, and 8 inhibitors, and substantial caspase 3, 6, and 8 activities were
induced by
NS-1 expression, there may have been interactions between NS-1 and the apoptotic pathways of the death receptors tumor necrosis factor receptor 1 and Fas
Chisaka et al., Rev Med Virol 2003
(Anemia...) :
The G ( 1 ) arrest is
induced by
NS1 expression prior to apoptosis induction in B19 infected cells, while the G(2) arrest is induced not only by infectious
B19 but also by UV-inactivated B19, which lacks the ability to express NS1
Munakata et al., Nihon Rinsho Meneki Gakkai Kaishi 2006
(Arthritis, Rheumatoid...) :
B19 is activated in infected cells, and functional viral protein
NS1 induces over production of inflammatory cytokine TNFalpha