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CDKN1C — CXCL12

Text-mined interactions from Literome

Zhao et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2012 (Myelodysplastic Syndromes) : The effect of SDF-1 on p57kip2 expression in bone marrow mononuclear cell ( BMMNC ) from MDS or normal controls was investigated in vitro, and difference between them was compared ... Moreover, SDF-1 increased p57kip2 expression in normal BMMNC in dose dependent manner, but BMMNC from MDS patients showed no response to SDF-1 ... Furthermore, SDF-1 induced p57kip2 expression in BMMNC, and the decreasing response of BMMNC to SDF-1 may contribute to the low expression of p57kip2 in MDS patients
Zhao et al., Hematology 2012 (Leukemia, Myeloid, Acute...) : SDF-1/CXCR4 signal is involved in decreased expression of p57kip2 in de novo MDS patients ... We also searched the role of stromal cell derived factor-1 (SDF-1)/CXCR4 signal in p57kip2 expression in vitro ... We also searched the role of stromal cell derived factor-1 (SDF-1)/CXCR4 signal in p57kip2 expression in vitro ... p57kip2 expression in bone marrow mononuclear cells of normal controls increased significantly when co-cultured with SDF-1 in vitro, which could be blocked by AMD3100, whereas SDF-1 only induced a mild increase in p57kip2 in MDS ... Reduced response to SDF-1 contributed to low expression of p57kip2 in MDS cases