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ANXA6 — CSF2
Text-mined interactions from Literome
Yamaguchi et al., J Biol Chem 1999
:
GM-CSF induced activation of not only
p70 S6 kinase, but also of MAP kinase
Lee et al., Exp Mol Med 2003
:
p70S6K was slightly
activated by
GM-CSF alone and markedly activated by SCF alone
Gomez-Cambronero et al., J Immunol 2003
:
Both
p70S6K enzymatic activity and T ( 421 ) /S ( 424 ) and T ( 389 ) phosphorylation are markedly
increased with
GM-CSF
Harada et al., J Interferon Cytokine Res 2004
:
In contrast, neutralizing
GM-CSF using anti-GM-CSF monoclonal antibody ( mAb ) significantly
inhibited IFN-gamma, TNF-alpha, and
IL-12p70 elicited by SCG
Oishi et al., Cytokine 2006
:
The
rhG-CSF induced a pre-PHx downregulation of the IL-12p70 protein levels, while also promoting the post-PHx reduction of the protein levels of
IL-12p70 and IFN-gamma
Harada et al., Microbiol Immunol 2006
(Leukopenia) :
Neutralizing
GM-CSF significantly
inhibited the induction of IFN-gamma, TNF-alpha and
IL-12p70 by SCG
Wong et al., J Immunol 2009
:
IL-12p70 production was produced predominantly by CD8alpha ( + ) DCs and plasmacytoid DCs, and
mediated by CD8 T cell derived cytokines IFN-gamma,
GM-CSF , TNF-alpha, and surface CD40L
Kenton et al., Biochim Biophys Acta 1989
:
Several phosphatase inhibitors failed to prevent macrophage
colony stimulating factor induced reduction of
p68 phosphorylation