UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to JAK3

FYN — JAK3

Pathways - manually collected, often from reviews:

BioCarta il-7 signal transduction: IL-7/IL-7Ra/IL-2R-gamma/JAK1/JAK3 complex (ITGA2B-Il7r-IL2RG-JAK1-JAK3) → FYN (modification, activates)
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3 complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3) → IL2/IL2R beta/gamma/JAK1/Fyn/JAK3/PI3K complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3-PIK3CA-PIK3R1) (modification, collaborate)
Augustine et al., Mol Cell Biol 1991
Evidence: assay, other species
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3 complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3) → PI3K complex (PIK3CA-PIK3R1) (modification, collaborate)
Augustine et al., Mol Cell Biol 1991
Evidence: assay, other species
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3/PI3K complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3-PIK3CA-PIK3R1) → PI3K complex (PIK3CA-PIK3R1) (modification, collaborate)
Augustine et al., Mol Cell Biol 1991
Evidence: assay, other species
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3 complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3) → IL2 (IL2) (modification, collaborate) Kobayashi et al., Proc Natl Acad Sci U S A 1993
Evidence: assay, physical interaction, other species
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3 complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3) → IL2R gamma/JAK3 complex (IL2RG-JAK3) (modification, collaborate)
Kobayashi et al., Proc Natl Acad Sci U S A 1993
Evidence: assay, physical interaction, other species
NCI Pathway Database IL2-mediated signaling events: IL2/IL2R beta/gamma/JAK1/Fyn/JAK3 complex (IL2RB-JAK1-FYN-IL2-IL2RG-JAK3) → IL2R beta/JAK1/Fyn complex (IL2RB-JAK1-FYN) (modification, collaborate)
Kobayashi et al., Proc Natl Acad Sci U S A 1993
Evidence: assay, physical interaction, other species
NCI Pathway Database IL2-mediated signaling events: IL2R gamma/JAK3 complex (IL2RG-JAK3) → IL2R beta/JAK1/Fyn complex (IL2RB-JAK1-FYN) (modification, collaborate)
Kobayashi et al., Proc Natl Acad Sci U S A 1993
Evidence: assay, physical interaction, other species