◀ Back to MSH6
ICAM1 — MSH6
Text-mined interactions from Literome
Moustafa et al., J Invest Dermatol 2002
:
We have previously shown that
alpha-MSH can
inhibit tumor necrosis factor-alpha stimulated
intercellular adhesion molecule 1 upregulation and nuclear factor kappaB (NFkappaB) transcription factor activation in melanocyte and melanoma cells
Scholzen et al., Endocrinology 2003
(Vasculitis) :
In addition,
alpha-MSH significantly
impaired the LPS induced
ICAM-1 and VCAM-1 mediated adhesion of lymphocytes to HDMEC monolayer in a functional adhesion assay
Hill et al., Peptides 2006
:
The present study confirms MC1R expression in cultured human dermal fibroblasts and reports that the
MSH peptides alpha-MSH and KP ( -D- ) V
inhibit TNF-alpha stimulated NF-kappaB activity and
ICAM-1 upregulation, consistent with an anti-inflammatory role
Morandini et al., J Cell Physiol 1998
(Melanoma) :
We conducted a study in order to evaluate the possible
effect of
MSH on
ICAM-1 expression in human cultured malignant and normal melanocytes
Hedley et al., Br J Dermatol 1998
(Melanoma) :
The maximum inhibitory response to alpha-MSH was obtained at around 10 ( -10 ) mol/L alpha-MSH when cells were coincubated with alpha-MSH and TNF-alpha for 24 h.
alpha-MSH had little or no effect on basal
ICAM-1 expression in melanocytes and the effects of alpha-MSH could be mimicked with 3-isobutyl-1-methylxanthine ( IBMX )