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CA2 — IRF6

Text-mined interactions from Literome

Ito et al., Microbiol Immunol 2000 : Results indicate that the addition of CaCl2 to suspensions of the Mg-bound R-form LPS result in a tighter binding of Ca2+ to the R-form LPS and the release of Mg2+ from the R-form LPS, and as a consequence, destroys the Mg2+ -induced ordered hexagonal lattice structure of the R-form LPS
Enomoto et al., Alcohol Clin Exp Res 2001 : In isolated Kupffer cells from rats treated with ethanol for 4 weeks, CD14, LPS induced intracellular Ca2+ , and TNF-alpha all were increased
Enomoto et al., Alcohol Clin Exp Res 2001 : The LPS induced increases in [Ca2+ ] i and tumor necrosis factor-alpha by Kupffer cells were also increased approximately 3-fold over control values, but they also returned to control levels
Enomoto et al., Gastroenterology 2002 (Liver Diseases, Alcoholic) : Furthermore, thalidomide abolished the LPS induced increase in CD14 expression and [ Ca2+ ] i elevation in KCs
Konno et al., Alcohol Clin Exp Res 2002 (Liver Cirrhosis, Alcoholic...) : In isolated Kupffer cells, LPS increased [Ca2+ ] ( i ) of Kupffer cells in control rats from basal levels ( 36 +/- 8 nmol/liter ) to 100 +/- 8 nmol/liter ... In contrast, the LPS induced [Ca2+ ] ( i ) elevation was approximately 3-fold greater in the group given EP treatment before 24 hr ( 305 +/- 17 nmol/liter ; p < 0.05 )
Choi et al., J Neurochem 2002 : Another mitochondrial agent cyclosporin A ( CsA ), which also acts at the permeability transition pore (PTP) of mitochondrial membrane but at a site different from the PBR, was ineffective in reducing either the LPS induced expression of COX-2 and TNF-alpha or the endotoxin increase in [ Ca2+ ] i
Tsukada et al., Alcohol Clin Exp Res 2003 (Liver Cirrhosis, Experimental) : LPS increased intracellular Ca2+ of KC in control rats from the basal level ( 26 +/- 6 nmol/liter ) to 280 +/- 18 nmol/liter
Maass et al., Am J Physiol Heart Circ Physiol 2005 (Burns...) : LPS ( 25 microg/5 x 10 ( 4 ) cells ) or BS ( 10 % by volume ) challenge for 18 h increased cardiomyocyte cytosolic and mitochondrial Ca2+ and promoted myocyte secretion of TNF-alpha, IL-1beta, and IL-6
Zhou et al., J Biol Chem 2006 : The results demonstrated that the LPS induced transient [ Ca2+ ] i increase is due to Ca2+ release and influx
Yu et al., J Immunol 2007 : It aggregated S. aureus and S. cerevisiae in a Ca2+ dependent manner and specifically bound to insoluble peptidoglycan and glucan, but not to LPS , lipoteichoic acid, and mannan
Kim et al., Arch Pharm Res 2008 (Calcium Signaling...) : In this study, we observed that LPS stimulated intracellular calcium increased in mouse bone marrow derived mast cells ( BMMC ), and rat C6 glioma and human HCT116 colon cancer cells and compared the LPS induced Ca2+ increases with the response by lysophosphatidic acid (LPA), a structurally related bioactive lysolipid ... In order to test involvement of signaling molecules in the LPS induced Ca2+ signaling, we used pertussis toxin ( PTX ), U73122, and 2-APB, which are specific inhibitors for G proteins, phospholipase C (PLC), and IP3 receptors, respectively
Wondergem et al., Am J Physiol Cell Physiol 2010 : Thus, we differentiated effects of LPS on [ Ca2+ ] i and Ca2+ oscillations by addition of utlrapure LPS, a TLR-4 ligand
Yamashiro et al., Biochem Biophys Res Commun 2010 : However, how intracellular free Ca2+ concentrations ([Ca2+]i) is increased in response to LPS and how they affect cytokine production are poorly understood ... Experiments using BAPTA/AM and EGTA, and Ca2+ imaging suggested that the LPS induced increase in [ Ca2+ ] i involves both the TRPV2 mediated intracellular and extracellular Ca2+ mobilizations
Kang et al., J Histochem Cytochem 1990 : Our previous studies indicate that bacterial lipopolysaccharide (LPS) enhances natural killer ( NK ) cell mediated cytotoxicity and increases intracellular calcium ( Ca2+ ) in hepatocytes ... In the present work, the effects of LPS and CAM on Ca2 ( + ) -ATPase and intracellular Ca2+ in human NK cells were studied by a combined technique of immunogold electron microscopy and ultracytochemistry ... Ca2 ( + ) -ATPase was localized in the plasma membrane of NK cells, and its activity was suppressed by LPS but was enhanced by CAM ... The results indicate that CAM is capable of blocking or reversing the inhibitory effect of LPS on Ca2 ( + ) -ATPase, and suggest that in human NK cells the plasma membrane associated Ca2 ( + ) -ATPase is responsible for extrusion of intracellular Ca2+
Prpic et al., J Immunol 1987 : When the total isomers of InsP3 were measured, levels rose about twofold in response to LPS or to lipid A and remained elevated for as long as 5 min. Lipid A, in the concentration range of 0.1 to 10 micrograms/ml, induced elevated intracellular levels of Ca2+ as quantified by fluorescence with Quin 2 or with Fura 2
Qu et al., J Periodontal Res 1995 (Peritonitis) : Effects of FMLP and LPS on [Ca2+ ] i of peritoneal exudate polymorphonuclear leukocytes following onset of inflammation
Kugaya et al., Brain Res 1995 (Brain Neoplasms...) : These results indicate that IL-1 beta and LPS inhibit 5-HT2 receptor mediated Ca2+ mobilization via pathways that include the activation of a tyrosine kinase and protein kinase C
Lee et al., J Immunol 1995 : Removing extracellular Ca2+ with EGTA inhibited LPS induction of TYKi, whereas increasing intracellular calcium with the calcium ionophore A23187 had little effect on the levels of the TYKi transcript
Kanayama et al., Biochem Biophys Res Commun 1995 : Kunitz-type trypsin inhibitor prevents LPS induced increase of cytosolic free Ca2+ in human neutrophils and HUVEC cells ... Preincubation of neutrophils and HUVEC cells with UTI inhibited increase of cytosolic free Ca2+ induced by LPS ... Increase of cytosolic free Ca2+ induced by LPS in the presence of EGTA was also inhibited by UTI
Portolés et al., Eur J Cell Biol 1994 : Concerning sinusoidal cells, LPS produced a significant increase of intracellular Ca2+ in both endothelial and Kupffer cells
Lichtman et al., Am J Physiol 1996 : Furthermore, LPS induced a late rise in intracellular free Ca2+ demonstrated by video microscopy of fura 2-loaded Kupffer cells
Malhotra et al., Biochem J 1996 : The binding of LPS to L-selectin is independent of serum and Ca2+ , and is blocked by antibodies to L-selectin and fucoidan
Xie et al., J Leukoc Biol 1997 : Determination of the intracellular Ca2+ levels demonstrates that LPS induced Ca2+ release is abrogated in propanil treated macrophages
Kanayama et al., Biochem Biophys Res Commun 1997 : The role of chondroitin sulfate chains of urinary trypsin inhibitor in inhibition of LPS induced increase of cytosolic free Ca2+ in HL60 cells and HUVEC cells ... Preincubation of HL60 cells and HUVEC cells with urinary trypsin inhibitor ( UTI ) inhibited increase of cytosolic free Ca2+ induced by LPS ... In contrast, an increase of cytosolic free Ca2+ induced by LPS was not inhibited by deglycosylated UTI, UTI treated with monoclonal antibody of chondroitin sulfate
Tawara et al., J Neurosci Res 1998 (Glioma) : To investigate the mechanisms by which lipopolysaccharide (LPS) affects Ca2+ signaling systems, we studied the effects of LPS on the serotonin ( 5-HT ) - or thrombin induced intracellular Ca2+ ( [ Ca2+ ] i ) increase in rat C6 glioma cells
Malhotra et al., Eur J Immunol 1998 : The binding of LPS to P-selectin is independent of Ca2+ , and is blocked by antibodies to P-selectin, lipid A and fucoidan
Song et al., Zhongguo Yao Li Xue Bao 1996 : Although LPS did not increase intracellular Ca2+ of PMo, intracellular Ca2+ was necessary for PAF release from rat PMo stimulated by LPS
Seabra et al., J Leukoc Biol 1998 (Calcium Signaling) : Because taurine, a ubiquitous sulfur containing beta-amino acid, acts similarly to glycine in neurons by causing hyperpolarization, it was hypothesized that taurine would act via a similar mechanism, blunting the LPS induced increase in [ Ca2+ ] i in Kupffer cells