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MSH4 — PLG
Text-mined interactions from Literome
Celis et al., Neurochem Int 1982
:
Since
PLG also
blocked the release of
MSH induced by the injection of haloperidol, it is suggested that its effect is not mediated by dopamine
Thody et al., Acta Endocrinol (Copenh) 1980
:
We have studied the
effect of
L-prolyl-L-leucyglycinamide (PLG) on the release of
melanocyte stimulating hormone ( MSH ) from the rat pituitary gland both in vitro and in vivo ... It is concluded that
PLG does not
affect the release of
alpha-MSH from the rat intermediate lobe
Vivas et al., Neuroendocrinology 1982
:
When 50 or 500 ng/ml of DA is added to the medium containing PLG concentrations it strengthened the inhibitory effect of PLG release, whereas the action of NE and PLG was additive ; at the highest tested concentration E ( 5,000 ng/ml ) blocked the inhibition of
MSH induced by
PLG
Scimonelli et al., Peptides 1982
:
Both spontaneous and potassium induced release were inhibited in a dose-response manner by the tripeptide Pro-Leu-Gly-NH2 ( PLG, or MIF-1 ) ; 0.04 microgram to 1 microgram
PLG inhibited the
alpha-MSH release but the lowest dose demonstrated a greater inhibitory effect ; high concentrations of PLG, on the other hand, did not modify either spontaneous or potassium evoked alpha-MSH release from the slices
Caballero et al., J Endocrinol 1993
:
When serum levels of progesterone were measured at 12.00 and 14.00 h in rats in which
alpha-MSH release was
blocked by
PLG or concentrated antiserum, a significant decrease was observed when compared with the levels of progesterone in control rats