◀ Back to IL1B
IL1B — PRL
Text-mined interactions from Literome
Gerlo et al., J Neuroimmunol 2005
:
PRL mRNA expression was
inhibited to a lesser extent by
IL-1beta , which decreased PRL mRNA levels to 58 % of control values
Lee et al., Cancer Res 2005
(MAP Kinase Signaling System) :
To delineate the signaling mechanism from 16-kDa PRL, we examined the
effect of 16-kDa
PRL on interleukin
IL-1beta-inducible iNOS expression, which is regulated by two parallel pathways, one involving IFN regulatory factor 1 (IRF-1) and the other nuclear factor-kappaB (NF-kappaB)
Skurlova et al., Endocr Regul 2006
:
Exogenous
IL-1beta induces its own expression, but not that of IL-6 in the hypothalamus and
activates HPA axis and
prolactin release
Yamaguchi et al., Endocrinol Jpn 1991
:
The
effects of human recombinant
interleukin-1 beta and -6 and tumor necrosis factor-alpha (TNF-alpha) on the releases of
PRL and dopamine were examined using monolayer cultures of rat pituitary cells and hypothalamic cells ... The release of
PRL from rat pituitary cells in 30 min was
increased about 2-fold ( p less than 0.05 ) by 10 ( 5 ) U/l
interleukin-1 beta , 10 ( 5 ) U/l interleukin-6 or 100 micrograms/l TNF-alpha
Tripathi et al., Int Immunol 2008
:
AG490, inhibitor of JAK2, down-regulated transcription factors c-jun and STAT1 and inhibited the
PRL induced IFN-gamma, TNF-alpha,
IL-1 beta and IL-12p40 production in macrophages
Sodhi et al., Growth Factors 2008
(Calcium Signaling...) :
The involvement of Ca++ signaling and p42/44 MAP kinase in regulation of
PRL induced
IL-1beta and TNF-alpha production by macrophages has also been investigated
Brunetti et al., Life Sci 1995
:
A possible role for nitric oxide but not for prostaglandin E2 in basal and
interleukin-1-beta induced
PRL release in vitro ... Now, we show experimental evidence of an involvement of NO in basal and
interleukin-1 beta induced
prolactin (PRL) release ... L-NG-nitro-arginine, an inhibitor of nitric oxide synthetase, and hemoglobin, a NO scavenger, impaired basal and
interleukin-1-beta induced
PRL release, while molsidomine, a NO donor, was able to release PRL and to amplify interleukin-1-beta induced PRL release, confirming a modulatory role for nitric oxide in pituitary hormone secretion ... On the other hand, no evidence regarding a possible role of prostaglandin E2 ( PGE2 ) in
IL-1beta induced
PRL release came out from our experiments
Turnbull et al., Neuroimmunomodulation 1995
:
The absence of a comparable change in the progesterone release rate of males infused with IL-1 beta, and the presence of marked surges of prolactin (PRL) in the females, suggests that
IL-1 beta altered ovarian function, and that the persistence of large corpora lutea
induced PRL release
Tseng et al., Mol Cell Endocrinol 1997
:
Here, we investigated the
effects of GH and
PRL on the expression of interleukin (IL)-1alpha,
IL-1beta and IL-6 in thymic stromal cells (TSC)