Gene interactions and pathways from curated databases and text-mining

◀ Back to IL4

IL4 — TNC

Text-mined interactions from Literome

Latijnhouwers et al., Arch Dermatol Res 2000 (Carcinoma, Basal Cell...) : In contrast, TNF alpha favoured expression of smaller tenascin-C transcripts, and IL-4 equally affected the expression of large and small tenascin-C mRNAs
Maqbool et al., Matrix Biol 2013 : ECM-regulatory matricellular proteins are synthesized by several myocardial cell types including CF. We investigated the effects of pro-inflammatory cytokines on matricellular protein expression in cultured human CF. cDNA array analysis of matricellular proteins revealed that interleukin-1a ( IL-1a, 10ng/ml, 6h ) down-regulated connective tissue growth factor ( CTGF/CCN2 ) mRNA by 80 % and up-regulated tenascin-C (TNC) mRNA levels by 10-fold in human CF, without affecting expression of thrombospondins 1-3, osteonectin or osteopontin