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ARG1 — VDR

Text-mined interactions from Literome

Ehrchen et al., FASEB J 2007 (Disease Susceptibility...) : Further analysis showed that this was a result of decreased production of nitric oxide by 1alpha,25 ( OH ) 2D3 treated macrophages due to Vdr dependent up-regulation of arginase 1 expression, which overrides NO production by Nos2
Kristjansson et al., J Clin Invest 1993 (Rickets) : This shows that Arg 271 directly affects the affinity of the VDR for its ligand and its conversion to leucine decreases its affinity for 1,25 ( OH ) 2D3 by a factor of 1,000