Gene interactions and pathways from curated databases and text-mining

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ATF4 — VIM

Text-mined interactions from Literome

Lian et al., J Biol Chem 2009 : DNA cotransfection and gel retardation demonstrated that vimentin inhibited the transactivation activity of ATF4 on osteocalcin by preventing it to bind OSE1, the ATF4 binding site on the osteocalcin promoter
Lian et al., J Biol Chem 2012 : Here we show that TGFß inhibits ATF4 dependent activation of Ocn by up-regulation of vimentin expression ... Interestingly, TGFß did not directly regulate the expression of ATF4 ; instead, it enhanced the expression of vimentin , a negative regulator of ATF4 , at the post-transcriptional level