Gene interactions and pathways from curated databases and text-mining

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COA6 — INS

Text-mined interactions from Literome

Komatsu et al., Diabetes 1999 : Taking these results together with previous results, we conclude that glucose augments Ca2+ stimulated insulin release, at least in part, by increasing malonyl-CoA and cytosolic LC-CoA
Andreolas et al., Diabetes 2002 : Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells
O'Rourke et al., J Biol Chem 2002 : However, in the presence of high glucose both insulin and leptin caused a significant increase in the activity of acyl-CoA : cholesterol O-acyltransferase ( ACAT ) combined with a significant reduction in the level of hormone-sensitive lipase (HSL)
Jason et al., J Biol Chem 1976 : Similar insulin dependent increases in microsomal fatty acid CoA ligase specific activities were observed using an assay based on the conversion of [ 3H ] CoA to fatty acyl- [ 3H ] CoA ... The insulin dependent increase in microsomal fatty acid CoA ligase specific activity was maximal in 2 to 5 min at 400 microunits/ml ... These data suggest that fatty acid CoA ligase activity is regulated in adipose tissue by insulin
Yaney et al., Diabetologia 2003 : These points highlight the important roles of NEFA, LC-CoA , and their esterified derivatives in affecting insulin secretion in both normal and pathological states
Achouri et al., Biochimie 2005 (Diabetes Mellitus, Experimental) : Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose : involvement of sterol regulatory element binding protein-1c
Wagenmakers et al., Clin Nutr 1996 : To assess whether insulin and glucose directly regulate malonyl-CoA in muscle, soleus muscles from young rats were incubated with insulin and glucose at various concentrations, and their content of malonyl-CoA was determined
Hansen et al., Biochem J 1991 : Induction of acyl-CoA binding protein and its mRNA in 3T3-L1 cells by insulin during preadipocyte-to-adipocyte differentiation
Xin et al., Cell Biol Int 2009 : To determine the signaling pathways and components involved in insulin mediated regulation of Acyl-CoA : cholesterol acyltransferase1 ( ACAT1 )
Xu et al., PLoS Genet 2012 : Insulin signaling regulates fatty acid catabolism at the level of CoA activation
Corkey et al., J Biol Chem 1989 : A role for malonyl-CoA in glucose stimulated insulin secretion from clonal pancreatic beta-cells
Munday et al., Biochem J 1987 : Insulin stimulated acetyl-CoA carboxylase activity measured in crude extracts of acini from high-fat fed rats, restoring it to values close to those of chow fed controls ... The effects of insulin on acetyl-CoA carboxylase activity and lipogenesis were not antagonized by adrenaline or dibutyryl cyclic AMP
Bartness et al., Am J Physiol 1986 (Body Weight...) : Insulin decreased the thermogenic potential of BAT [ cytochrome oxidase activity ( COA ) ] in intact controls and diabetics ; in the latter, insulin restored COA independent of BAT innervation
Lemmen et al., Eur J Clin Invest 1983 (Hyperlipoproteinemia Type IV) : Insulin increased acetyl-CoA carboxylase activity and incorporation of [ 2-14C ] -acetate in lipids in both cell types, but with no difference between normal and FHT lines
Buko et al., Vopr Med Khim 1981 : Insulin activated and hydroxythiamine inhibited the liver tissue acetyl-CoA-carboxylase
Moule et al., Biochem J 1995 : Whereas wortmannin largely abolished the effects of insulin on glucose utilization and acetyl-CoA carboxylase activity, it was without effect on the stimulation of pyruvate dehydrogenase
Jochen et al., Biochim Biophys Acta 1995 : Cerulenin was also found to inhibit insulin stimulated glucose uptake and acetyl-CoA carboxylase activity
Szutowicz et al., Neuroreport 1994 (Diabetes Mellitus, Experimental) : Streprozotocin diabetes and extracerebral insulin affect acetyl-CoA and acetylcholine metabolism in the brain
Duan et al., J Appl Physiol 1993 : This study was designed to determine the effects of glucose and insulin on malonyl-CoA , the potent inhibitor of carnitine palmitoyltransferase I, in the gastrocnemius/plantaris muscle group
Wu et al., Biochim Biophys Acta 1993 (Liver Neoplasms, Experimental) : The effects of tetradecylthioacetic acid ( TTA ), insulin and dexamethasone on palmitoyl-CoA synthetase activity and its mRNA both in 7800 C1 hepatoma cells and cultured rat hepatocytes were studied
Moore et al., Int J Biochem Cell Biol 1996 : In this study, the effects of insulin and oxalyl thiolesters on pyruvate dehydrogenase, beta-oxidation, and acyl-CoA hydrolase activities in mitochondria from rat epididymal adipocytes are compared