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EPHB2 — GJA1

Text-mined interactions from Literome

Yao et al., Kidney Int 2000 : Using two structurally unrelated PI3K inhibitors, wortmanin and LY294002, both tyrosine phosphorylation of Cx43 and activation of ERK stimulated by PDGF were largely blocked
Polontchouk et al., FASEB J 2002 (MAP Kinase Signaling System) : Mitogen activated protein kinase inhibition revealed that ERK1/2 was critical for up-regulation of Cx43 in response to ET-1, whereas both ERK and p38 signal pathways were involved in the regulation of Cx43 by AT-II
Melchheier et al., Biochem Biophys Res Commun 2005 : As a consequence of ERK activation, Cx43 was phosphorylated, resulting in a downregulation of GJC
Lin et al., Curr Eye Res 2007 (Diabetes Mellitus, Experimental) : PKC-gamma activation was measured by enzyme activity assay and by Western blotting to show autophosphorylation on Thr514. Cellular insulin-like growth factor-1 (IGF-1), PKC-gamma phosphorylation of Cx43 on Ser368, and activation of phospholipase C-gamma 1 ( PLC-gamma 1 ), extracellular signal regulated kinase ( ERK1/2 ), and caspase-3 were determined by Western blotting
Simecková et al., Toxicological sciences : an official journal of the Society of Toxicology 2009 : PCB 153 contributed to extracellular signal regulated kinases 1 and 2 ( ERK1/2 ) -dependent accumulation of hyperphosphorylated Cx43-P3 form, thus indicating that ERK1/2 activation by PCB 153 might contribute to its effects on Cx43 internalization or degradation
Chang et al., Biomaterials 2009 : The results showed that Pep-1 coated QDs, which escaped from the endo-/lysosome degradation, could activate the F-actin assembly and the ERK dependent phosphorylation of Cx43
Wang et al., BMC cell biology 2011 : AGE-BSA down-regulated Cx43 expression in HAEC, mainly through reduced Cx43 transcription, and the process involved activation of ERK and p38 MAPK
Lin et al., Neurochem Int 2013 : HYS-32 induced activation of PKC, ERK , and JNK, and co-treatment with the PKC inhibitor Go6976 or the ERK inhibitor PD98059, but not the JNK inhibitor SP600125, prevented the HYS-32 induced increase in Cx43 expression and GJIC
Wang et al., Mol Cell Biochem 2013 (MAP Kinase Signaling System) : Subsequently, extracellular signal regulated kinase ( ERK ) was inhibited with PD98059 to analyze the role of ERK in modulating CX43 expression after LPS preconditioning