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CD8A — IL5
Text-mined interactions from Literome
Braun et al., Eur J Immunol 2000
:
In mixed lymphocyte cultures ( MLC ), the presence of
CD8 ( + ) T cells in the responding cell population
inhibited the secretion of
IL-5
Lee et al., J Interferon Cytokine Res 2000
(Mast-Cell Sarcoma) :
Dose dependent and schedule dependent
effects of
interleukin-12 on antigen-specific
CD8 responses
Soldan et al., J Immunol 2003
(Multiple Sclerosis, Chronic Progressive...) :
The increase in
IL-5 was primarily
due to an increase in CD4 ( + ) and
CD8 ( + ) T cells, the increase in IL-10 was primarily due to an increase in CD64 ( + ) monocytes/macrophages with some effect in T cells, while the decrease in TNF-alpha was primarily due to a decrease in CD8 ( + ) T cells
Cao et al., Cell Mol Immunol 2004
(Carcinoma...) :
Global gene expression profiling in
interleukin-12 induced activation of
CD8 ( + ) cytotoxic T lymphocytes against mouse mammary Carcinoma
Willemsen et al., J Immunol 2006
(Melanoma) :
The introduction of a mutated cysteine motif in CD8alpha, which prevents its binding to LCK and linker for activation of T cells, did not adversely affect expression and T cell cytotoxicity, but counteracted the
CD8alpha mediated down-regulation of IL-4 and
IL-5 , but not IL-10
Wells et al., J Allergy Clin Immunol 2007
(Inflammation...) :
Adoptive transfer of transgenic antigen-specific
CD8 , but not CD4, cells resulted in increased IL-12 levels and
reduced IL-13 and
IL-5 levels in bronchoalveolar lavage fluid, coupled with substantially reduced airway eosinophilia after repeated allergen inhalation, a process mimicked by intranasal administration of IL-12 and inhibited by anti-IL-12 antibody
Chaput et al., Gut 2009
(Adenocarcinoma...) :
Finally,
interleukin 6 and TGF beta 1 synergistically
induced the generation of
CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Ohnishi et al., J Allergy Clin Immunol 2009
(Inflammation...) :
Adoptive transfer of U0126 treated
CD8 ( + ) T cells into sensitized mice before secondary allergen challenge
resulted in significant decreases in AHR, eosinophilic inflammation, goblet cell metaplasia, and
IL-5 and IL-13 levels in bronchoalveolar lavage fluid of recipient mice
Ma et al., Scand J Immunol 2011
(Colonic Neoplasms) :
This study aims to investigate the
role of tumour derived Foxhead box P3 (Foxp3) ( +
) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific
CD8 ( + ) T cells
Höllsberg et al., Proc Natl Acad Sci U S A 1995
:
CD8 T-cell stimulation with the wild-type peptide antigen
led to activation of p56lck kinase activity,
interleukin 2 secretion, cytotoxicity, and clonal expansion