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MSN — NGF
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Kim et al., Neurochem Int 2010
:
We have previously shown that in PC12 cells : ( 1 ) high extracellular KCl induces
moesin phosphorylation, an event which was dependent on chloride channel activation, and ( 2 )
NGF induces moesin phosphorylation which is required for neurite outgrowth ... Also, the
NGF induced
moesin phosphorylation was suppressed by NPPB
Jeon et al., Neurochem Int 2010
:
NGF induced
moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells ...
NGF rapidly
induced the phosphorylation of
moesin at Thr-558 in PC12 cells which was dependent on PI3K and Rac1