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PRKCA — RHO

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: RHO — PRKCA (in vitro) Kennedy et al., Neuron 2001*, Lee et al., Protein Sci 2002*, Ohguro et al., J Biol Chem 1996*, Greene et al., J Biol Chem 1997*
• IRef Hprd Interaction: RHO — PRKCA (in vivo) Kennedy et al., Neuron 2001*, Lee et al., Protein Sci 2002*, Ohguro et al., J Biol Chem 1996*, Greene et al., J Biol Chem 1997*

Text-mined interactions from Literome

Mehta et al., J Biol Chem 2001 : Using inhibitors and dominant negative mutants, we found that Rho activation was regulated by PKC-alpha
Holinstat et al., J Biol Chem 2003 : Because Rho activation is also dependent on protein kinase Calpha (PKCalpha) , we addressed the possibility that PKCalpha can also induce Rho activation secondary to the phosphorylation of p115RhoGEF ... Studies were made using human umbilical vein endothelial cells in which we addressed the mechanisms of PKCalpha induced Rho activation and its consequences on actin cytoskeletal changes
Pan et al., J Cell Physiol 2005 (Cardiomegaly) : Using adenoviral mediated gene transfer of wild-type ( WT ) and dominant negative ( DN ) mutants of PKCalpha and delta, we found that stretch induced activation of Rho GTPases and phosphorylation of Rho-GDI were mainly regulated by PKCalpha
Radeff et al., J Bone Miner Res 2004 : Rho and Rho kinase are involved in parathyroid hormone stimulated protein kinase C alpha translocation and IL-6 promoter activity in osteoblastic cells
Stamatovic et al., J Biol Chem 2006 : PKCalpha and Rho, but not PKCzeta and Rho, interacted at the level of Rho, with PKCalpha being a downstream target for Rho