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IL21 — STAT4

Text-mined interactions from Literome

Chin et al., Nature 2002 (Listeriosis...) : Furthermore, Rip2 deficiency results in impaired interferon-gamma production in both TH1 and natural killer cells, attributed in part to defective interleukin-12 induced Stat4 activation
Strengell et al., J Immunol 2003 : Similarly, IL-21 induced the binding of STAT1, STAT3, and STAT4 to these elements
Suto et al., J Immunol 2006 : Moreover, the repression of Eomes expression by IL-21 is not due to an indirect effect of IL-21 on the expression of IFN-gamma or STAT4 and is independent of STAT1 and T-bet expression
Casey et al., J Immunol 2007 : Here, we show that IL-21 does not require STAT4 to stimulate development of cytolytic activity
Karpuzoglu et al., Endocrinology 2009 : Signal transducer and activation of transcription ( STAT ) 4beta, a shorter isoform of interleukin-12 induced STAT4 , is preferentially activated by estrogen
Watford et al., J Exp Med 2008 (Toxoplasmosis, Animal) : We investigated the potential roles of Tpl2 in T cells and found that it was induced by interleukin-12 in human and mouse T cells in a Stat4 dependent manner
Thierfelder et al., Nature 1996 : Requirement for Stat4 in interleukin-12 mediated responses of natural killer and T cells