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IL4 — MED17

Text-mined interactions from Literome

Speziani et al., Eur J Immunol 2007 : IL-2, IFN-gamma and IL-4 inhibit TRAP and bone resorption activities contrary to IL-10, which enhances both activities
Yu et al., J Biol Chem 2009 : To determine whether IL-4 regulates TRAP promoter activity, RAW264.7 cells were transfected with a TRAP promoter-luciferase reporter ... Knockdown of NFATc1 by short interfering RNA caused TRAP expression to be down-regulated, and ectopic expression of NFATc1 abrogated the IL-4 induced down-regulation of TRAP
Kasono et al., Bone Miner 1993 (Bone Resorption) : The minimum effective inhibitory concentration was 0.01 ng/ml, and 1 ng/ml IL-4 completely inhibited TRAP ( + ) MNC formation