Gene interactions and pathways from curated databases and text-mining

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CASR — PTHLH

Text-mined interactions from Literome

Ardeshirpour et al., Bone 2006 : The calcium sensing receptor regulates PTHrP production and calcium transport in the lactating mammary gland
Mamillapalli et al., J Endocrinol 2010 : The calcium sensing receptor couples to Galpha ( s ) and regulates PTHrP and ACTH secretion in pituitary cells
Vanhouten et al., Best Pract Res Clin Endocrinol Metab 2013 : In contrast, in breast cancer cells the CaSR upregulates PTHrP production ... A switch in G-protein usage underlies the opposing effects of the CaSR on PTHrP expression in normal and malignant breast cells