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FUT1 — IL8
Text-mined interactions from Literome
Sugita et al., Res Commun Mol Pathol Pharmacol 1999
:
We investigated the
effect of
FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines,
interleukin-6 (IL-6) and interleukin-8 (IL-8), by monocytes stimulated with lipopolysaccharide (LPS) ... We investigated the
effect of
FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and
interleukin-8 (IL-8) , by monocytes stimulated with lipopolysaccharide (LPS) ... The productions of both IL-6 and
IL-8 , measured by enzyme linked immunosorbent assay, were significantly
inhibited by
FUT at the concentration of 1 to 100 microg/ml in a dose dependent manner ... Furthermore, the expressions of IL-6 and
IL-8 mRNAs were also
inhibited by
FUT-175
Kikuchi et al., Res Commun Mol Pathol Pharmacol 1995
:
IL-8 production by PMN and vascular endothelial cells stimulated with lipopolysaccharide (LPS) was
inhibited by
FUT-175