Gene interactions and pathways from curated databases and text-mining

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INS — PLCG1

Text-mined interactions from Literome

Crouch et al., Immunol Cell Biol 2000 : However, both EGF and insulin stimulated the accumulation of phospholipase Cgamma1 at the actin arc, which was coincident with the EGF receptor in the case of insulin- stimulated cells
Eichhorn et al., Biochem Biophys Res Commun 2001 : Insulin activates phospholipase C-gamma1 via a PI-3 kinase dependent mechanism in 3T3-L1 adipocytes
Eichhorn et al., Endocrinology 2002 : In this study, we confirmed that the insulin receptor and PLC-gamma1 are physically associated in hIRcB fibroblasts, insulin stimulates PLC-gamma1 enzyme activity, and inhibition of PLC activity impairs activation of ERK
Kwon et al., J Cell Biol 2003 : Insulin increased PLCgamma1 tyrosine phosphorylation at Tyr-783 and its colocalization with the IR in punctated structures enriched in cortical actin at the dorsal plasma membrane
Myers et al., Ann N Y Acad Sci 1995 : Moreover, PDGF, but not insulin , caused tyrosine phosphorylation of phospholipase C gamma in HIR 3.5 cells