Gene interactions and pathways from curated databases and text-mining

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ANG — MPO

Text-mined interactions from Literome

Ji et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2008 : To investigate the effects of angiotensin II (Ang II) on mRNA and protein expressions of toll-like receptor 4 (TLR4) and myeloperoxidase (MPO) activity in RAW264.7 cells, and explore its pro-inflammatory and pro-atherosclerotic mechanisms ... In addition, Ang II concentration-dependently elevated MPO activity in RAW264.7 cells ( P < 0.01 ), and LPS also enhanced MPO activity of RAW264.7 cells ( P < 0.01 ), but the TLR4 blocker significantly antagonized the effect of Ang II on MPO activity ( P < 0.01 ) ... Ang II upregulates TLR4 expressions, and induces MPO secretion via TLR4 in RAW264.7 cells, which mediate the pro-inflammatory effect of Ang II to contribute formation and development of atherosclerosis
Ji et al., Yao Xue Xue Bao 2009 : This study is to investigate the effect of fenofibrate on angiotensin II (Ang II) induced toll-like receptor 4 (TLR4) expression, myeloperoxidase (MPO) activity and expression in murine macrophage line RAW264.7 cells and explore its anti-inflammatory mechanism
Ji et al., Nan Fang Yi Ke Da Xue Xue Bao 2009 : To investigate the effect of rosiglitazone on angiotensin II (Ang II) induced mRNA and protein expressions of toll-like receptor 4 (TLR4) and myeloperoxidase (MPO) activity in RAW264.7 cells to explore its anti- inflammatory and anti-atherosclerotic mechanisms