Gene interactions and pathways from curated databases and text-mining

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NOS3 — NPY6R

Text-mined interactions from Literome

Xu et al., Hypertension 2004 : An Src kinase inhibitor, pp2 , and MEK inhibitor, PD98059, blocked the ERK1/2 phosphorylation and eNOS expression
Jin et al., J Biol Chem 2005 : Gab1 phosphorylation as well as activation of Akt and eNOS by flow was inhibited by the Src kinase inhibitor PP2 ( 4-amino-5- ( 4-chlorophenyl ) -7- ( t-butyl ) pyrazolo [ 3,4-d ] pyrimidine ) and VEGFR2 kinase inhibitors SU1498 and VTI, suggesting that flow mediated Gab1 phosphorylation is Src kinase dependent and VEGFR2 dependent
Slomiany et al., Inflammopharmacology 2008 : Moreover, the stimulatory effect of leptin on the acinar cell cNOS activity was inhibited not only by PP2 , but also by Akt inhibitor, SH-5, while wortmannin had no effect
Slomiany et al., J Physiol Pharmacol 2008 : Moreover, the stimulatory effect of leptin on the mucosal cells cNOS activity was inhibited not only by PP2 , but also by Akt inhibitor, SH-5