Gene interactions and pathways from curated databases and text-mining

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NPPA — NPR2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Yasunari et al., Hypertension 1992 : Although a PKC inhibitor and downregulation of PKC by long-term incubation of cells with phorbol esters blocked the phorbol ester induced desensitization of the ANP-B receptor response, they did not block the ANP induced desensitization of the ANP-B receptor response
Cootauco et al., Am J Obstet Gynecol 2008 : The objective of the study was to identify the effect of atrial natriuretic peptide (ANP) on uterine contractility, production of ANP, and natriuretic peptide receptor ( NPR ) expression in human myometrial tissue
Ralat et al., J Biol Chem 2011 : Conversely, reduced IDE expression enhances the stimulation of NPR-A and NPR-B by ANP and CNP, respectively ... Additionally, the cleavages of ANP and BNP by IDE render them active with NPR-B and a reduction of IDE expression diminishes the ability of ANP and BNP to stimulate NPR-B
Chang et al., Nature 1989 : The ANP-B receptor is preferentially activated by porcine brain natriuretic peptide rather than human alpha-ANP , whereas the ANP-A receptor responds similarly to both natriuretic peptides