◀ Back to FAS

FAS — PDCD4

Text-mined interactions from Literome

Zhang et al., J Immunol 1999 : Restimulation of Ag receptors on peripheral T lymphocytes induces tyrosine phosphorylation based signaling cascades that evoke Fas ligand expression and induction of Fas mediated programmed cell death
Su et al., J Immunol 2000 (Diabetes Mellitus, Type 1...) : These results provide evidence that Fas/FasL mediated programmed cell death plays a significant role in the pathogenesis of autoimmune diabetes
Kimura et al., J Biol Chem 2000 (Prostatic Neoplasms) : Activation of either tumor necrosis factor receptor 1 or Fas induces a low level of programmed cell death in LNCaP human prostate cancer cells
Schaefer et al., J Pediatr Surg 2000 (Brain Neoplasms...) : Ceramides ( known stimuli of apoptosis downstream from the CD95-receptor complex ) also were used to test whether apoptosis would be induced in neuroblastoma cell cultures resistant to CD95 mediated programmed cell death
Yasuda et al., Lab Anim 2000 : Fas ( lpr ) ( lpr ) and Fas ( lprcg ) ( lpr ( cg ) ) are allelic mutations of the Fas gene that is involved in apoptosis or programmed cell death
Comi et al., Neurology 2000 (Multiple Sclerosis) : Fas ( CD95 ) triggers programmed cell death and is involved in shutting off the immune response
Semra et al., J Neuroimmunol 2001 (Inflammation...) : The cellular caspase-inhibitory protein FLIP has been recently identified as a potent regulator of T lymphocyte susceptibility to Fas mediated programmed cell death ( apoptosis )
DeFranco et al., Diabetes 2001 (Autoimmune Diseases...) : Fas ( CD95 ) triggers programmed cell death and is involved in cell mediated cytotoxicity and in shutting off the immune response
Hsu et al., J Biomed Sci 2001 (Diabetes Mellitus, Experimental...) : Fas ( CD95 ) and Fas ligand ( FasL/CD95L ) are involved in programmed cell death and the regulation of host immune responses
Perlman et al., Nat Cell Biol 2001 (Lymphoma, B-Cell) : Here we have used a screen for proteins that interact physically with the cytoplasmic domain of the type II TGF-beta receptor to isolate the gene encoding Daxx - a protein associated with the Fas receptor that mediates activation of Jun amino-terminal kinase (JNK) and programmed cell death induced by Fas
Ahmed et al., J Virol 2002 (Acute Disease...) : By transfecting cells with a construct expressing the Pst-Mlu segment of the LAT, encompassing the LAT exon 1, the stable 2.0-kb intron, and 5 ' part of exon 2, we confirmed that this region was able to diminish the onset of programmed cell death initiated by anti-Fas and camptothecin treatment
Shain et al., J Immunol 2002 (Hematologic Neoplasms) : These data show that adhesion of anchorage independent cells to fibronectin provides a novel mechanism of resistance to CD95 mediated programmed cell death by regulating the cellular localization and availability of c-FLIP ( L )
Ugolini et al., J Neurosci 2003 : To investigate the role of Fas in programmed cell death and pathological situations, we used several mutant mice deficient for Fas signaling and made a novel transgenic FADD-DN ( FAS associated death domain-dominant negative ) strain
Lichter et al., Genomics 1992 : Binding of anti-APO-1 antibody to the APO-1 antigen induces programmed cell death ( apoptosis )
Cattaruzza et al., FASEB J 2004 (Neoplasm Invasiveness...) : In fact, G1-overexpressing cells appeared resistant to both cytotoxic drug induced and Fas dependent programmed cell death , and this resistance implicated mitochondrial apoptotic genes
Boehm et al., Curr Mol Med 2006 (Skin Diseases) : Experimental evidence suggests a role for Bcl-2 and CD95L in the inhibition of programmed cell death in UV-induced skin cancer or malignant melanoma cells
Bi et al., BMC medical genetics 2007 (Autoimmune Diseases...) : Molecular and biochemical assessment of these mutant Fas ligand proteins were carried out by expressing the mutant FasL cDNA in mammalian cells and analysis its effects on Fas mediated programmed cell death
Krieg et al., Mol Immunol 2009 : Moreover, RIP2 has been shown to interact with the CARD of caspase-1 and to induce IL-1beta maturation as well as in the induction of CD95 mediated programmed cell death by enhancing caspase-8 activity
Ju et al., Nature 1995 : Fas ( CD95 ) /FasL interactions required for programmed cell death after T-cell activation
Wilson et al., Eur J Immunol 1996 (Lymphoma) : While in most situations Fas ligation activates programmed cell death , on resting T lymphocytes it can co-stimulate proliferation with the T cell receptor (TCR)/CD3 complex
Deiss et al., EMBO J 1996 : Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
Sytwu et al., Immunity 1996 (Lymphoproliferative Disorders) : The roles of Fas/APO-1 ( CD95 ) and TNF in antigen induced programmed cell death in T cell receptor transgenic mice
Gulbins et al., J Biol Chem 1996 : Genetic and pharmacological inhibition of Ras or Rac 1 and Rac 2 stimulation blocks Fas induced apoptosis, pointing to an important function of a Ras and Rac protein regulated signaling pathway in Fas mediated programmed cell death
Gulbins et al., Immunology 1996 : Fas induced programmed cell death is mediated by a Ras regulated O2- synthesis ... Genetic inhibition of Ras by transfection of transdominant inhibitory N17Ras blocked Fas mediated ROI synthesis and programmed cell death ... Likewise, the antioxidants N-acetyl-cysteine and N-t-butyl-phenylnitrone abolished Fas induced cell death, pointing to an important role for Ras triggered ROI synthesis in Fas mediated programmed cell death
Starling et al., J Exp Med 1997 : The interaction of Fas ( CD95 ), a member of the tumor necrosis factor receptor (TNFR) family, and its ligand ( FasL ) triggers programmed cell death ( apoptosis ) and is involved in the regulation of immune responses
Egle et al., Br J Haematol 1997 (Multiple Myeloma) : We studied eight myeloma cell lines for the presence of Bcl-2, which inhibits apoptosis, of Bax, which counteracts Bcl-2, of Bcl-x ( L ) and Bcl-x ( S ), which act in an anti- and pro-apoptotic fashion, respectively, and of Apo-1/Fas , which induces programmed cell death , when activated by the Apo-1/Fas ligand or the relevant monoclonal antibody ( mab )
Prasad et al., Proc Natl Acad Sci U S A 1997 : In addition to providing costimulatory signals for cell proliferation, ligation of both TNFR1 and Fas can result in programmed cell death or apoptosis
Gulbins et al., Proc Natl Acad Sci U S A 1997 (Ion Channel Gating) : The n-type K+ channel ( n-K+, Kv1.3 ) in lymphocytes has been recently implicated in the regulation of Fas induced programmed cell death
Huang et al., Immunity 1997 : Fas/APO-1 ( CD95 ) ligation activates programmed cell death , a cellular process that plays an important role in the maturation of the host immune response
Skarstein et al., Scand J Immunol 1997 (Autoimmune Diseases) : The mutation is leaky, allowing for low levels of the APO-1/Fas ( CD95 ) receptor and partial activity of Fas/Fas ligand mediated programmed cell death in this strain
Wagner et al., Nature 1998 (HIV Infections) : The cytolytic pathway involves calcium dependent exocytosis of perforin and granzyme proteases, as well as Fas mediated programmed cell death , whereas the noncytolytic pathway involves the release of chemokines that prevent viral entry
Yang et al., Int Immunol 1998 : Activation of T cell hybridomas in vitro induces rapid Fas-Fas ligand (FasL) mediated programmed cell death ( apoptosis )
Wang et al., Nat Genet 1998 (Leukemia, Promyelocytic, Acute) : We also found that Pml is essential for induction of programmed cell death by Fas , tumour necrosis factor alpha (TNF), ceramide and type I and II interferons ( IFNs )