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PRG3 — PTH

Text-mined interactions from Literome

Suzuki et al., Clinical calcium 2006 : We also found that calcitonin and parathyroid hormone markedly enhanced proteoglycan synthesis in these cells
Iannotti et al., J Orthop Res 1990 : Mechanism of action of parathyroid hormone induced proteoglycan synthesis in the growth plate chondrocyte ... Parathyroid hormone also induced a 30-50 % increase in proteoglycan synthesis ... From this data we postulate that the stimulation of proteoglycan synthesis in growth plate chondrocytes by PTH is mediated by the breakdown of membrane phosphoinositides, which results in the production of IP3 and an increase in ionized intracellular calcium
Kato et al., Endocrinology 1988 : These observations suggest that in addition to the transient rise of cAMP, other biochemical changes are required for elaboration of the effect of PTH on proteoglycan synthesis
Fukuo et al., J Biochem 1986 : PTH increased the activity of ornithine decarboxylase [ ODC ; EC 4.1.1.17 ], a rate limiting enzyme of polyamine biosynthesis, and proteoglycan synthesis in chondrocytes pretreated with TPA as well as in normal chondrocytes ... The dose-response curve for ODC induction by PTH was parallel to that of PTH stimulated proteoglycan synthesis both in TPA treated chondrocytes and in normal chondrocytes
Sebert et al., Nephrologie 1982 (Hypophosphatemia, Familial...) : Some recent in vitro experiments have shown, however, that 24,25 ( OH ) 2D3 intervenes in the stimulation of proteoglycan synthesis, inhibition of PTH , vitamin A and heparin induced resorption, whereas 1,25 ( OH ) 2D3 does not