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KRAS — RELA

Text-mined interactions from Literome

Kwon et al., Biochem Biophys Res Commun 2008 : In support of this, compared with wild type Akt1, the dominant negative Akt1 mutant was decreased in its nuclear expression, reducing the Ki-Ras induced NF-kappaB transcriptional activation ... The complete inhibition of Ki-Ras induced NF-kappaB activation, however, could only be obtained by combined treatment with wortmannin and proteasome inhibitor-1
Meylan et al., Nature 2009 (Adenocarcinoma...) : Concomitant loss of p53 ( also known as Trp53 ) and expression of oncogenic Kras ( G12D ) resulted in NF-kappaB activation in primary mouse embryonic fibroblasts
Bassères et al., Cancer Res 2010 (Cell Transformation, Neoplastic...) : Using lung cell lines expressing oncogenic K-Ras, we show that NF-kappaB is activated in these cells in a K-Ras dependent manner and that NF-kappaB activation by K-Ras requires inhibitor of kappaB kinase beta ( IKKbeta ) kinase activity