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NUP43 — TGFB3
Text-mined interactions from Literome
Chaturvedi et al., Endocrinology 2004
:
Estradiol and
TGF-beta3 alone moderately
activated MAPK
p44/42 ; together they produced marked activation of MAPK p44/42 ... Pretreatment of FS cells with an MAPK kinase 1/2 inhibitor or with protein kinase C inhibitors suppressed the activation of MAPK
p44/42 , bFGF release, and protein level increases, all of which were
induced by
TGF-beta3 and estradiol
Kanno et al., Horm Metab Res 2005
(MAP Kinase Signaling System) :
We previously reported that
transforming growth factor-beta ( TGF-beta )
activates p44/p42 mitogen activated protein ( MAP ) kinase and p38 MAP kinase, resulting in the stimulation of vascular endothelial growth factor ( VEGF ) synthesis in osteoblast-like MC3T3-E1 cells
Chaturvedi et al., J Pharmacol Exp Ther 2005
(MAP Kinase Signaling System) :
Ethanol and
TGF-beta3 alone moderately
increased activation of MAPK
p44/42 , but together they produced marked activation of MAPK p44/42 ... Pretreatment of FS cells with a mitogen activated protein kinase kinase 1/2 inhibitor or with a protein kinase C ( PKC ) inhibitor suppressed the
TGF-beta3 and ethanol
actions on MAPK
p44/42 activation and bFGF release ... Furthermore, the MAPK
p44/42 activation by
TGF-beta3 and ethanol was blocked by overexpression of Ras N17, a dominant negative mutant of Ras p21