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IL1A — TLR5

Text-mined interactions from Literome

Yamamoto et al., Nature 2004 : Transcription of IkappaBzeta is rapidly induced by stimulation with TLR ligands and interleukin-1 (IL-1)
Szczepański et al., Eur Arch Otorhinolaryngol 2006 (Cholesteatoma, Middle Ear...) : TLR-ligand binding results in cell signal transduction and subsequent production of various proinflammatory cytokines such as IL-1 and TNF-alpha
van Beelen et al., Immunity 2007 (Bacterial Infections...) : MDP enhanced obligate bacterial Toll-like receptor ( TLR ) agonist induction of IL-23 and IL-1 , which promoted IL-17 expression in T cells
Croker et al., Proc Natl Acad Sci U S A 2008 (Autoimmune Diseases...) : TLR induced TNF and IL-1 production are normal in macrophages derived from spin mice
Böni-Schnetzler et al., Endocrinology 2009 : We conclude that FFA and TLR stimulation induce proinflammatory factors in islets and that IL-1RI engagement results in signal amplification
Dewamitta et al., Infect Immun 2010 : The Toll-like receptor ( TLR ) /MyD88 signaling pathway was exclusively required for the expression of pro-IL-1 alpha , independently of LLO mediated cytoplasmic entry of L. monocytogenes
Carvalho et al., Mucosal Immunol 2011 (Colitis...) : In vivo, flagellin induced sIL-1Ra, but not IL-1ß , was absolutely dependent upon TLR5 expressed on non-hemopioetic cells
Chávez-Sánchez et al., Lipids in health and disease 2010 : The activation of CD14, TLR4 , and TLR2 by mmLDL induces IL-1ß , IL-6, and IL-10 secretion in human monocytes and macrophages
Dasu et al., Am J Physiol Endocrinol Metab 2011 (Diabetes Mellitus, Type 2...) : Silencing TLR2, TLR4 , and p47phox with small inhibitory RNAs ( siRNAs ) significantly reduced superoxide release, NF-?B activity, IL-1ß , and MCP-1 secretion in HG and palmitate treated THP-1 cells
Carta et al., J Biol Chem 2011 : TLR engagement induces an effective redox response with increased ROS generation followed by a sustained antioxidant response, parallelled by efficient IL-1ß secretion
Das et al., Immunol Cell Biol 2012 (Leishmaniasis, Visceral) : In this report, we demonstrated that later stages of L. donovani infection rendered tolerance to macrophages, leading to incapability for the production of inflammatory cytokines like tumor necrosis factor (TNF)-a and interleukin (IL)-1ß in response to TLR stimulation
den Dunnen et al., Blood 2012 (Bacterial Infections...) : First, TLR-Fc?RIIa costimulation strongly increased transcription of pro-IL-1ß and IL-23p19
Kavathas et al., Mucosal Immunol 2013 : In addition, we demonstrate that Ct-induced IL-1ß production and secretion by the trophoblast is independent of TLR2, TLR4 , MyD88, and the Nalp3/ASC inflammasome
Perugorria et al., Hepatology 2013 (Liver Cirrhosis...) : KCs lacking Tpl2 display defects with TLR induction of cytokines interleukin (IL)-1ß , IL-10, and IL-23
Gupta et al., Cell Signal 2013 (Glioma...) : Importantly, ß-defensin-3 prevented IL-1ß induced HLA-G, TLR4 , HMGB1 expression and release of pro-inflammatory mediators
He et al., J Immunol 2013 : Furthermore, they challenge the idea that the ATP-P2X7 axis is critical for TLR induced IL-1ß production via the Nlrp3 inflammasome in vivo