We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MDM2

MDM2 — TCF23

Text-mined interactions from Literome

Blagosklonny et al., Oncogene 2001 : Thus, Mdm-2 targets the p53 tumor suppressor for ubiquitin dependent degradation by the proteasome, but, in addition, the p53 transcription factor induces Mdm-2 , thus, establishing a feedback loop
Vargas et al., Adv Cancer Res 2003 (Neoplasms) : In response to stress, however, p53 is not affected by Mdm2 and functions as a transcription factor that induces the transcription of Mdm2 as well as of genes involved in growth control or apoptosis
Carroll et al., Cancer Res 2008 (Carcinoma, Renal Cell...) : The oncogene HDM2 has been implicated in the regulation of the transcription factor , hypoxia inducible factor ( HIF )
Xu et al., Cell 2009 (Retinoblastoma) : Interestingly, retinoblastoma cell MDM2 expression was regulated by the cone-specific RXRgamma transcription factor and a human-specific RXRgamma consensus binding site, and proliferation required RXRgamma, as well as the cone-specific thyroid hormone receptor-beta2