Gene interactions and pathways from curated databases and text-mining

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EPHB2 — EPS8

Text-mined interactions from Literome

Maa et al., Oncogene 2001 (Cell Transformation, Neoplastic...) : Overexpression of p97Eps8 leads to cellular transformation : implication of pleckstrin homology domain in p97Eps8 mediated ERK activation
Robinet et al., FASEB J 2007 (Myocardial Reperfusion Injury) : EPs interaction with S-Gal triggered NO release and activation of PI3-kinase/Akt and ERK1/2 in human coronary endothelial cells ( HCAECs ) and rat neonatal cardiomyocytes ( RCs )
Auciello et al., J Cell Sci 2013 : Eps8 interacts with the clathrin mediated endocytosis machinery and depletion of Eps8 inhibits FGFR trafficking and immediate Erk signalling