Gene interactions and pathways from curated databases and text-mining

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EPHB2 — GAS6

Text-mined interactions from Literome

Goruppi et al., Oncogene 1999 : We further show evidence that Gas6 stimulation of serum starved NIH3T3 cells results in a transient ERK , JNK/SAPK and p38 MAPK activation
Motomura et al., Biochem Biophys Res Commun 2007 : Gas6 signaling activated the phosphorylation of ERK1/2 , SAPK/JNK, and Akt, but not p38 MAPK
Son et al., J Mol Cell Cardiol 2013 (Atherosclerosis...) : We also found that downregulation of Gas6 by TM/EGF receptor axis was mediated by ERK in VSMC calcification
Lee et al., Biochem Biophys Res Commun 2013 (MAP Kinase Signaling System...) : In this study, we found that Gas6 induced the activation of JNK and ERK1/2 signaling in cancer cells expressing Axl, resulting in the phosphorylation of activator protein-1 (AP-1) transcription factors c-Jun and ATF-2, and induction of Slug
Allen et al., Mol Endocrinol 1999 : Gas6/Ark stimulated the extracellular signal regulated kinase, ERK , and the serine-threonine kinase, Akt, a downstream component of the phosphoinositide 3-kinase (PI3-K) pathway