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EPHB2 — GAS6
Text-mined interactions from Literome
Goruppi et al., Oncogene 1999
:
We further show evidence that
Gas6 stimulation of serum starved NIH3T3 cells
results in a transient
ERK , JNK/SAPK and p38 MAPK activation
Motomura et al., Biochem Biophys Res Commun 2007
:
Gas6 signaling
activated the phosphorylation of
ERK1/2 , SAPK/JNK, and Akt, but not p38 MAPK
Son et al., J Mol Cell Cardiol 2013
(Atherosclerosis...) :
We also found that downregulation of
Gas6 by TM/EGF receptor axis was
mediated by
ERK in VSMC calcification
Lee et al., Biochem Biophys Res Commun 2013
(MAP Kinase Signaling System...) :
In this study, we found that
Gas6 induced the activation of JNK and
ERK1/2 signaling in cancer cells expressing Axl, resulting in the phosphorylation of activator protein-1 (AP-1) transcription factors c-Jun and ATF-2, and induction of Slug
Allen et al., Mol Endocrinol 1999
:
Gas6/Ark stimulated the extracellular signal regulated kinase,
ERK , and the serine-threonine kinase, Akt, a downstream component of the phosphoinositide 3-kinase (PI3-K) pathway