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GP9 — IL6
Text-mined interactions from Literome
D'Addario et al., J Mol Biol 2001
:
To our knowledge this is the first report showing that the binding of a herpesvirus envelope
glycoprotein to CR2 on human B cells
results in the activation of the NF-kappaB transcription factor leading to the upregulation of
IL-6 gene expression in these lymphocytes
Merino et al., Am J Cardiol 2004
(Coronary Disease) :
It was found that
glycoprotein IIb/IIIa inhibition significantly blocked postangioplasty CRP increases in all patients but
blocked IL-6 increases only in patients carrying the -174 GG genotype
Ha et al., J Leukoc Biol 2005
:
Binding of pregnancy-specific
glycoprotein 17 to CD9 on macrophages
induces secretion of IL-10,
IL-6 , PGE2, and TGF-beta1
Sundar et al., Proc Natl Acad Sci U S A 1991
:
Human immunodeficiency virus
glycoprotein ( gp120 ) infused into rat brain
induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses
Kuzuhara et al., Eur J Pharmacol 2006
(Liver Failure) :
We examined whether the 22beta-methoxyolean-12-ene-3beta,24 ( 4beta ) -diol ( ME3738 ) -mediated selective induction of
interleukin-6 increased alpha1-acid
glycoprotein and serum amyloid A expression, and whether these proteins protected against liver injury in vitro and in vivo
Kino et al., J Allergy Clin Immunol 2007
:
TB-2-081 suppressed
IL-6 induced mRNA expression of alpha1-acid
glycoprotein , alpha2-macroglobulin, and beta-fibrinogen in and secretion of the C-reactive protein by rat primary hepatocytes
Suzuki et al., FEBS Lett 2008
:
Sendai virus F
glycoprotein induces
IL-6 production in dendritic cells in a fusion independent manner ... These results suggest that F
glycoprotein is
required for
IL-6 production in DCs
Chen et al., Am J Physiol Heart Circ Physiol 2009
(Atherosclerosis) :
Blockade of the synergism by soluble
glycoprotein 130Fc/soluble IL-6 receptor, as well as the
induction of synergistic
IL-6 production by costimulation of SMCs with IL-1, TNF-alpha, and hyper-IL-6, suggested the involvement of IL-6 trans signaling
Lee et al., Inflamm Res 2009
(Inflammation...) :
In addition, ZPDC
glycoprotein ( 200 microg/ml ) not only diminished the production of superoxide anion, hydrogen peroxide, and nitric oxide, but also
suppressed the expression of pro-inflammatory cytokines ( IL-1 beta,
IL-6 , and TNF-alpha ) and proteins ( iNOS, COX-2, and MMP-9 ) in LPS- stimulated RAW 264.7 cells
Oh et al., J Cell Biochem 2010
(Anaphylaxis...) :
Our results revealed that the CTB
glycoprotein in the presence of DEHP
inhibits the release of histamine and expression of interleukin (IL)-4,
IL-6 , and TNF-alpha in RBL-2H3 cells ... The results from these experiments indicated that the CTB
glycoprotein inhibits release of histamine and expressions of IL-4,
IL-6 , and TNF-alpha via down regulations of PKC/MAPK and NF-kappaB on the stage of mast cell degranulation induced by DEHP
Dai et al., International journal of molecular sciences 2011
:
Interleukin-6 and tumor necrosis factor-a levels in the lipopolysaccharide induced peripheral blood mononuclear cell supernates were significantly
reduced by spermine and/or a2-Heremans-Schmid
glycoprotein
Won et al., Mol Cell Biol 1990
(Liver Neoplasms, Experimental) :
Expression of the rat alpha 1-acid
glycoprotein gene is
stimulated by interleukin-1 (IL-1) and
interleukin-6 (IL-6) and is synergistically enhanced by the combination of the two
Taga et al., Cell 1989
:
We report here that an 80 kd single polypeptide chain ( IL-6-R ) is involved in IL-6 binding and that
IL-6 triggers the association of this receptor with a non-ligand binding membrane
glycoprotein , gp130
Kojima et al., J Pharmacobiodyn 1986
(Neoplasms, Experimental) :
Furthermore, this serum
glycoprotein was found to
enhance glucose consumption and
interleukin-1 production and cytotoxic activities of mouse peritoneal macrophages
Geiger et al., J Biol Chem 1988
(Liver Neoplasms, Experimental) :
Induction of alpha 1-acid
glycoprotein by recombinant human
interleukin-1 in rat hepatoma cells
Itoh et al., Dig Dis Sci 1994
:
The secretion of alpha 1-acid
glycoprotein by hepatocytes was stimulated and that of albumin was
inhibited by combinations of dexamethasone and monokines, especially by dexamethasone and
interleukin-6
Barraud et al., Biol Cell 1995
:
The secretion of alpha 1-acid
glycoprotein was largely
induced by dexamethasone alone or dexamethasone and recombinant human
interleukin-6
Weston et al., Transpl Immunol 1995
(Kidney Failure, Chronic) :
E-Selectin is a 115-kDa cell surface
glycoprotein transiently expressed on vascular endothelium in
response to
interleukin-1 and tumour necrosis factor-alpha with a peak in expression at four hours
Fournier et al., Hepatology 1994
:
These results show that ( a ) phenobarbital acts directly on hepatocytes by increasing alpha 1-acid glycoprotein gene expression and ( b ) this effect is mediated by a specific mechanism independent of pathways involved in alpha 1-acid
glycoprotein induction by
interleukin-1 , interleukin-6 and glucocorticoids
Herbert et al., FEBS Lett 1993
:
Endotoxin ( LPS ),
interleukin-1 beta (IL-1) and tumor necrosis factor-alpha (TNF)
increased the expression of tissue factor, a membrane anchored
glycoprotein that initiates blood coagulation on the surface of cultured bovine aortic endothelial cells ( ABAE ) and human monocytes
Andrejko et al., Crit Care Med 1996
(Sepsis) :
To test the hypothesis that after cecal ligation and puncture in the rat, there is increased expression of the tumor necrosis factor
(TNF)/interleukin-1 dependent , acute-phase reactant alpha 1-acid
glycoprotein in the liver, and that this change correlates temporally with increased abundance of TNF-alpha in the hepatic parenchyma but not with circulating concentrations of TNF-alpha
Combates et al., Cell Growth Differ 1997
:
Involvement of the transcription factor
NF-IL6 in phorbol ester induction of
P-glycoprotein in U937 cells
Hallek et al., Exp Hematol 1997
:
Binding of
interleukin-6 to its receptor (IL-6R) induces the association of the IL-6R alpha chain ( IL-6Ralpha ) with a 130-kDa transmembrane
glycoprotein , gp130
Kurth et al., J Immunol 1999
:
Activation of the signal transducer
glycoprotein 130 by both
IL-6 and IL-11 requires two distinct binding epitopes
Guillonneau et al., Biochim Biophys Acta 1999
:
Hepatocyte differentiation of WIF-B cells includes a high capacity of
interleukin-6 mediated induction of alpha 1-acid
glycoprotein and alpha 2-macroglobulin