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HSPA8 — SMAD2

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of nuclear SMAD2/3 signaling: MSG1/HSC70 complex (CITED1-HSPA8) → SMAD2/SMAD2/SMAD4 complex (SMAD2-SMAD4) (modification, inhibits)
  Yahata et al., J Biol Chem 2000, Simonsson et al., J Biol Chem 2006, Tu et al., J Biol Chem 2007, Shioda et al., Proc Natl Acad Sci U S A 1998, Pouponnot et al., J Biol Chem 1998
  Evidence: mutant phenotype, assay, reporter gene, physical interaction