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Tai et al., J Neurochem 2001
:
Forskolin treatment of PC12 cells also rapidly increased nuclear levels of Egr-1 and the catalytic subunit of PKA ( PKA-C ), with the rise in PKA-C preceding that of Egr-1
Kim et al., J Cell Biochem 2008
:
The siRNA mediated inhibition of PKA and ERK1 resulted in significant reduction of EX-4 induced Egr-1 expression
Ginty et al., J Biol Chem 1991
:
Here we demonstrate that both cAMP- and calcium mediated induction of c-fos and egr1 are dependent on PKA activity
Chang et al., J Cell Biochem 2012
(MAP Kinase Signaling System) :
Collectively, quercetin induced EGR-1 expression is largely dependent on PKA and partly on p38 MAPK pathway, and SRE sites of EGR-1 promoter are involved in quercetin induced EGR-1 transcriptional activity
Ye et al., EMBO J 1996
:
The binding of WT1ZF - KTS to an EGR1 consensus binding site was also inhibited by prior PKA and PKC phosphorylation