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BCL2 — TAT

Text-mined interactions from Literome

Wang et al., Virology 1999 : Results from these studies reveal effects of HIV-1 Tat on Bcl-2 expression and provide a putative mechanism by which endogenously expressed Tat affects cellular survival through the up-regulation of Bcl-2
Macho et al., Oncogene 1999 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive...) : These pre-apoptotic events were associated with the cleavage of the caspase-3, while the expression of Bcl-2, Bcl-XL and Bax proteins was not affected by the presence of Tat
Zhang et al., J Biomed Sci 2002 (HIV Infections) : Bcl-2 upregulation by HIV-1 Tat during infection of primary human macrophages in culture
Adams et al., Synapse 2010 : In addition, select components of apoptotic pathway signaling appear more sensitive to estrogen receptor ( ER ) activation, as the addition of ER antagonist ICI 182780 reversed estrogen downregulation of Bax and caspase 3, while estrogen effects on Tat induced Bcl-2 and caspase 9 expression were maintained
Chambers et al., ACS Chem Biol 2011 : Tat-Sab ( KIM1 ) selectivity was also demonstrated in anisomycin stressed HeLa cells where Tat-Sab ( KIM1 ) prevented Bcl-2 phosphorylation, cell death, loss of mitochondrial membrane potential, and superoxide generation but not c-Jun phosphorylation
Sgadari et al., International journal of vascular medicine 2011 : Upregulation of Bcl-2 expression by combined FGF-2 and Tat occurs also in vitro, and this protects human primary endothelial cells from programmed cell death
Zauli et al., Blood 1995 : In this report, we investigated the effect of either endogenous or exogenous Tat on Bcl-2 proto-oncogene expression and cell survival in Jurkat T-cell lines and primary peripheral blood mononuclear cells ... We also observed a specific correlation between tat induced Bcl-2 gene expression and inhibition of apoptosis induced by serum withdrawal