Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ICAM1
→
CX3CR1
(increases, ICAM1 Activity)
Evidence: We transfected CX3CR1-interfering RNA or control siRNA into cultured HUVECs and exposed these cells to s-FKN. HUVECs with CX3CR1 knockdown expressed less ICAM-1 mRNA and protein compared with cells transfected with control siRNA (Figure 4a and 4b), indicating that FKN does activate ICAM-1 in ECs through CX3CR1.