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CPOX — PI3
Text-mined interactions from Literome
Lee et al., J Biol Chem 2003
:
LY294002, dominant negative ( DN )
phosphatidylinositol 3-kinase (PI3K) , or AKT ( DN )
inhibited NFkappaB activation, p65 transactivation, and
cyclooxygenase-2 (COX-2) expression induced by lauric acid or constitutively active ( CA ) TLR4
Araki et al., Free Radic Biol Med 2005
:
PLA2,
COX , PKC, NADH dehydrogenase, and XO inhibitors
prevented the CA-induced ROS generation but not ERK 1/2,
PI 3 K, p38 MAPK, and MLCK inhibitors