Gene interactions and pathways from curated databases and text-mining

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CPOX — PI3

Text-mined interactions from Literome

Lee et al., J Biol Chem 2003 : LY294002, dominant negative ( DN ) phosphatidylinositol 3-kinase (PI3K) , or AKT ( DN ) inhibited NFkappaB activation, p65 transactivation, and cyclooxygenase-2 (COX-2) expression induced by lauric acid or constitutively active ( CA ) TLR4
Araki et al., Free Radic Biol Med 2005 : PLA2, COX , PKC, NADH dehydrogenase, and XO inhibitors prevented the CA-induced ROS generation but not ERK 1/2, PI 3 K, p38 MAPK, and MLCK inhibitors