Gene interactions and pathways from curated databases and text-mining

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MAP2K6 — RNF19A

Text-mined interactions from Literome

Cong et al., Proc Natl Acad Sci U S A 1999 (MAP Kinase Signaling System) : c-Abl induced p38 activation was primarily mediated by mitogen activated protein kinase kinase ( MKK ) 6
Edlund et al., Mol Biol Cell 2003 (Prostatic Neoplasms) : Transforming growth factor-beta1 ( TGF-beta ) -induced apoptosis of prostate cancer cells involves Smad7 dependent activation of p38 by TGF-beta activated kinase 1 and mitogen activated protein kinase kinase 3
Fu et al., J Cell Sci 2006 (MAP Kinase Signaling System) : The phosphorylation of p38alpha induced by NP60 requires upstream activity of p38alpha MAP kinase, MAP kinase kinase 6 (MKK6) or MKK4
Cuenda et al., EMBO J 1996 (Leukemia, Monocytic, Acute) : However, under our assay conditions, SAPKK3 was the major activator of RK/p38 detected in extracts prepared from stress- or interleukin-1 stimulated epithelial ( KB ) cells, from bacterial lipopolysaccharide and tumour necrosis factor alpha stimulated THP1 monocytes or from rabbit skeletal muscle