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CEBPD — IRF6
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Kravchenko et al., J Biol Chem 2003
(Inflammation) :
Cells lacking IKKi are normal in activation of the canonical NF-kappaB pathway but fail to induce
C/EBPdelta activity and transcription of C/EBP and C/EBP-NF-kappaB target genes in
response to
LPS
Uto et al., Oncol Rep 2007
:
LPS induced activation of all of these factors and 6-MITC
suppressed LPS induced activation of AP-1,
C/EBPdelta , CREB, but not NF-kappaB
Djoko et al., J Agric Food Chem 2007
(Inflammation) :
In further, when these stilbenoids were subjected to monitoring their inhibitory effectiveness on
LPS induced transcription factor expressions of
C/EBPdelta and C/EBPbeta, only C/EBPdelta expressions were reduced
Liu et al., Cell Mol Life Sci 2007
:
Role of transcriptional factors Sp1, c-Rel, and c-Jun in
LPS induced
C/EBPdelta gene expression of mouse macrophages ... Here, it was suggested that
C/EBPdelta gene was
activated by
lipopolysaccharide (LPS) through transcription factors Sp1, c-Rel, and c-Jun ... Treatment of cells with ERK/JNK/p38 inhibitors or NF-kappaB inhibitor inhibited the
LPS induced
C/EBPdelta gene expression by inhibiting c-Jun, c-Rel, and p300 binding to DNA ... Our findings provide a better understanding of
LPS induced
C/EBPdelta gene expression
Liu et al., J Cell Biochem 2010
:
Inhibition of
LPS induced
C/EBP delta by trichostatin A has a positive effect on LPS induced cyclooxygenase 2 expression in RAW264.7 cells ... We found no significant difference in NF-kappaB activation and ERK1/2 phosphorylation, but
LPS induced
C/EBP delta expression was completely abolished after TSA treatment of LPS treated cells