Gene interactions and pathways from curated databases and text-mining

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EBP — PTGS2

Text-mined interactions from Literome

Yeo et al., J Biol Chem 2003 : In addition, Cox-2 promoter-luciferase reporters with alterations in predicted cis acting transcriptional regulatory elements revealed that C/EBP , Ets-1, NF-kappaB, and CREB binding sites are essential for optimal Cox-2 expression in response to CpG DNA
Lee et al., Br J Pharmacol 2003 : The effects of sauchinone on the inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-alpha) and cyclooxygenase 2 (COX-2) gene expression and on the activation of transcription factors, nuclear factor-kappaB (NF-kappaB), CCAAT/enhancer binding protein (C/EBP) , activator protein-1 (AP-1) and cAMP-response element binding protein ( CREB ) were determined in Raw264.7 cells as part of the studies on its anti-inflammatory effects
Healy et al., Am J Physiol Cell Physiol 2008 : Deletion and mutation analyses of the human cox-2 promoter reveal that the CCAAT/enhancer binding protein (C/EBP) and activator protein-1 (AP-1) predominantly contribute to the shear induced cox-2 promoter activity