Gene interactions and pathways from curated databases and text-mining

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PADI4 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Liu et al., Apoptosis 2006 : PADI4 increases tumor suppressor p53 and its downstream p21 to control cell cycle
Li et al., Mol Cell Biol 2008 : Regulation of p53 target gene expression by peptidylarginine deiminase 4 ... Here, we report that peptidylarginine deiminase 4, a histone citrullination enzyme, is involved in the repression of p53 target genes