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CIITA — CNTN2
Text-mined interactions from Literome
Tosi et al., Proc Natl Acad Sci U S A 2006
:
Direct sequestering of CBP or p300 is not the primary mechanism by which
CIITA causes suppression of
Tax-2
Tosi et al., J Virol 2011
:
CIITA inhibitory action on Tax-1 correlated with the nuclear localization of CIITA and was independent of the transcription factor NF-YB, previously involved in
CIITA mediated inhibition of
Tax-2 of HTLV-2 ... Instead,
CIITA severely
impaired the physical and functional interaction of
Tax-1 with the cellular coactivators p300/CBP associated factor (PCAF), cyclic AMP-responsive element binding protein ( CREB ), and activating transcription factor 1 (ATF1), which are required for the optimal activation of HTLV-1 promoter