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CD36 — JUN

Text-mined interactions from Literome

Katayama et al., Int J Radiat Oncol Biol Phys 2008 : In addition, we found that IR of human macrophages resulted in c-Jun N-terminal kinase activation and that c-Jun N-terminal kinase inhibition suppressed IR-induced CD36 expression and the subsequent foam cell formation and aggregation
Lee et al., Life Sci 2009 : Up-regulation of SR-A and CD36 by resistin resulted from activation of AP-1 and PPARgamma, respectively, and this was confirmed by the lack of activation of either after AP-1 inhibition using curcumin or SP600125, or PPARgamma inhibition using GW9662, respectively
Oh et al., Circulation 2009 (Diabetes Mellitus, Type 2...) : 1,25 ( OH ) ( 2 ) D ( 3 ) downregulation of c-Jun N-terminal kinase activation reduced peroxisome proliferated activated receptor-gamma expression, suppressed CD36 expression, and prevented oxidized low-density lipoprotein derived cholesterol uptake
Riek et al., J Steroid Biochem Mol Biol 2010 (Atherosclerosis...) : 1,25 ( OH ) 2D3 downregulation of c-Jun N-terminal kinase activation reduced PPARgamma and CD36 expression, and prevented oxLDL derived cholesterol uptake
Li et al., Int J Mol Med 2013 : The reduced CD36 expression following kaempferol treatment involved the inhibition of c-Jun-activator protein-1 (AP-1) nuclear translocation ... The reduced CD36 expression following kaempferol treatment involved the inhibition of c-Jun-activator protein-1 (AP-1) nuclear translocation ... The inhibition of AP-1 using the inhibitor, SP600125, confirmed this involvement, as the AP-1 inhibition significantly augmented the kaempferol induced reduction in CD36 expression ... In conclusion, the c-Jun-AP-1 dependent downregulation of CD36 and the HO-1 dependent upregulation of ABCG1, SR-BI and ABCA1 may mediate the beneficial effects of kaempferol on foam cell formation