Lee et al., Mol Cancer Res 2004
(Breast Neoplasms...) :
Stromal cell derived factor 1alpha ( SDF-1alpha ; CXCL12 ) stimulation of breast cancer cells resulted in phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and activation of the FKHRL1 transcription factor
Wu et al., J Neurochem 2009
:
The CXCR4 antagonist ( T140 ) or inhibitors for G proteins ( Pertussis toxin ) and phosphoinositide 3-kinase (PI3K) ( LY294002 ) abolished CXCL12 mediated NPC proliferation and phosphorylation of Akt-1 and FOXO3a