Gene interactions and pathways from curated databases and text-mining

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CA2 — OPRM1

Text-mined interactions from Literome

Samways et al., Biochem J 2003 : We next determined whether mu-opioid receptor activation might increase [Ca2+ ] i by sensitizing the Ins P3 receptor to Ins P3
Gris et al., Molecular pain 2010 : In contrast to stimulation of MOR1, stimulation of MOR1K leads to increased Ca2+ levels as well as increased nitric oxide ( NO ) release
Kligman et al., J Neurochem 1986 : We show that this modulator of phosphorylation (MOP) enhances Ca2+- and phospholipid dependent protein kinase ( C kinase ) phosphorylation of this 90K substrate
Wandless et al., Br J Anaesth 1996 : This response was naloxone-reversible, and the delta opioid agonist [ D-Pen2,5 ] enkephalin had no effect on [Ca2+ ] i, suggesting the fentanyl induced Ca2+ response was entirely mediated by the mu opioid receptor