Gene interactions and pathways from curated databases and text-mining

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F3 — IRF6

Text-mined interactions from Literome

Xuereb et al., Thromb Haemost 2000 (MAP Kinase Signaling System) : Tissue Factor (TF) , the receptor for plasma VII/VIIa and the initiator of blood coagulation, is inducible in vascular smooth muscle cells ( SMCs ) by growth factors and bacterial lysopolysaccharides (LPS) and is expressed in vivo after vascular injury
Osterud et al., Blood Coagul Fibrinolysis 1990 : Furthermore, nordihydroguaiaretic acid ( NDGA ), a lipoxygenase inhibitor, had an effect on the LPS induced thromboplastin synthesis which varied from no inhibition in individuals insensitive to LPS ( ` low responders ' ), up to 80 % inhibition in the person with the highest response ( ` high responder ' ) to LPS ... Intake of acetylsalicylic acid caused a 50 % increment of LPS induced thromboplastin synthesis, and this effect was mediated by platelets
Hansen et al., J Intern Med Suppl 1989 : Stimulation of blood with a low concentration of lipopolysaccharides (LPS) revealed a 40 % suppression of LPS induced thromboplastin synthesis in the monocytes after 8 weeks of CLO intake
Hansen et al., Thromb Haemost 1989 : The effect of lipopolysaccharides (LPS) on generation of thromboxane A2 and thromboplastin activity in whole blood of males, females and females on oral contraceptives
Carlsen et al., Clin Exp Immunol 1987 : Recombinant gamma-interferon ( r gamma-IFN ) has contrasting effects on thromboplastin (TPL) synthesis induced in monocytes ( M ) and endothelial cells by bacterial lipopolysaccharide (LPS) , phorbol ester ( TPA ), and phytohaemagglutinin ( PHA )
Sitrin et al., J Immunol 1984 : The results of this study demonstrate that PGE is required for the LPS mediated enhancement of rabbit alveolar macrophage associated tissue thromboplastin and that PGE can stimulate the expression of PCA by appropriately conditioned cells
Böhrer et al., J Clin Invest 1997 (Sepsis) : Tissue factor , a gene under regulatory control of NFkappaB, was induced by LPS