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IL11 — VWF

Text-mined interactions from Literome

Denis et al., Blood 2001 (Disease Models, Animal...) : Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models ... This led to further evaluation of the effect of recombinant human ( rh ) IL-11 on vWf and factor VIII (FVIII) secretion
Ragni et al., Haemophilia 2008 (von Willebrand Diseases) : Recombinant IL-11 increases VWF levels in humans with mild VWD, justifying future clinical trials to determine its potential in preventing or reducing bleeding in this patient population