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Text-mined interactions from Literome

Zhang et al., J Neurochem 1999 (Glioma...) : Inhibition of p38 MAPK had no significant effect on opioid induced ERK activation, indicating that p38 MAPK activity was not required for ERK activation, though its stimulation preceded ERK activation
Zimmermann et al., J Biol Chem 2001 (MAP Kinase Signaling System) : Proteasome- and p38 dependent regulation of ERK3 expression
Park et al., J Biol Chem 2001 (Reperfusion Injury) : In summary, post-ischemic JNK and p38 ( but not ERK1/2 ) activation was markedly reduced in a model of kidney ischemic preconditioning that was established in the mouse
Page et al., Am J Physiol Lung Cell Mol Physiol 2001 : Chemical inhibitors of p38 induced modest ERK phosphorylation and activation
Maulon et al., Oncogene 2001 (MAP Kinase Signaling System) : We show that thrombin mediated ERKs activation requires both PTK and PKC activities, whereas p38 MAPK activation is dependent only on PTKs. Thrombin induced ERK and p38 MAPK activation was more pronounced in p56Lck deficient cells indicating that this PTK exerts a negative control on MAPK activity
Barouch et al., J Leukoc Biol 2001 (MAP Kinase Signaling System) : NGF induced phosphorylation and activation of extracellular signal regulated kinase, Erk1/Erk2 and c-Jun amino-terminal kinase, whereas it did not induce phosphorylation of p38 mitogen activated protein kinase
Sheth et al., Surgery 2001 (MAP Kinase Signaling System) : These data show that p38 inhibition enhances ERK activity during endotoxemia
Kushida et al., Am J Physiol Cell Physiol 2001 (MAP Kinase Signaling System) : Activation of p38 was weak compared with that of JNK, and ERK was not activated at all
Park et al., Hepatology 2002 (Carcinoma, Hepatocellular...) : However, inhibition of the JNK pathway suppressed p38 but induced transient ERK activation
Bolla et al., J Vasc Res 2002 : This contraction requires p38 MAPK activation, but did not involve ERK1/2 MAPK activation although both were activated
Kim et al., J Korean Med Sci 2002 (MAP Kinase Signaling System) : It inhibited ERK phosphorylation, but did not inhibit p38 phosphorylation
Rumora et al., Biochem Biophys Res Commun 2003 (MAP Kinase Signaling System) : A specific p38 inhibitor SB 203580 also stimulated ERK activation and cell survival
Niles et al., Cancer Lett 2003 (MAP Kinase Signaling System...) : Although resveratrol did not alter the phosphorylation of p38 or JNK MAP kinases in either cell line, it induced phosphorylation of ERK1/2 in A375, but not in SK-mel28 cells
Burlando et al., Cell Physiol Biochem 2003 (Carcinoma, Hepatocellular) : Cell pre-incubation with p38 inhibitors indicated that ERK activation by H ( 2 ) O ( 2 ) is prevented by concomitant activation of p38
Mukhopadhyay et al., J Biol Chem 2004 (Carcinoma, Squamous Cell...) : Interestingly blocking p38 MAPK activity enhanced ERK1/2 phosphorylation, suggesting reciprocal regulation between the ERK1/2 and p38 MAPK pathways
Zauli et al., Blood 2004 (Bone Resorption) : Of note, the addition of TRAIL to RANKL plus M-CSF did not affect ERK1/2 but it profoundly inhibited p38/MAPK phosphorylation
Pan et al., J Cell Physiol 2005 (Cardiomegaly) : The phosphorylation of ERK and JNK induced by overexpression of WT PKCalpha, and the phosphorylation of p38 induced by WT PKCdelta, were regulated by Rho GTPases
Choi et al., Biochem Biophys Res Commun 2004 : A specific inhibitor of JNK, SP600125, abolished paclitaxel induced HO-1 mRNA expression, whereas PD98059, a specific inhibitor of ERK , and SB203580, a specific inhibitor of p38 , had no significant effect
Han et al., Cell Tissue Res 2004 : These alterations in protein level of adhesion molecules and in the phosphorylation of mitogen activated protein kinases by glucose were blocked by inhibition of PKC or p38 but were synergistically increased by the inhibition of ERK
Baines et al., J Mol Cell Cardiol 2005 : While a fair amount of discordance exists in the literature, we will weigh evidence that largely suggests a pro-apoptotic regulatory role for the p38 mitogen activated protein kinase, JNK, and PKCdelta, yet an anti-apoptotic regulatory role for ERK , PKCepsilon, JAK, and calcineurin in the myocardium
Shih et al., Food Chem Toxicol 2005 (Adenocarcinoma...) : In addition, the malvidin treatment significantly increased the p38 kinase expression and inhibited the ERK activity, and the effects of malvidin on caspase-3 activation were blocked, respectively, by the ERK and p38 inhibitors
Yeh et al., Carcinogenesis 2005 (Carcinoma, Hepatocellular...) : SB203580, a specific inhibitor of p38 and PD98059, a specific inhibitor of ERK , abolished sulforaphane induced MT protein expression, whereas SP600125, a specific inhibitor of JNK, had no significant effect
Han et al., FEBS Lett 2005 : While extracellular signal regulated kinase ( ERK ) and p38 activation was detected in Prx II ( -/- ) MEF, ERK and c-Jun N-terminal kinase (JNK) activation was detected in Prx II ( -/- ) skin
Wang et al., Blood 2006 (MAP Kinase Signaling System...) : Thus, our results suggested that tumor induced p38 MAPK activation and ERK inhibition in DCs may be a new mechanism for tumor evasion and that regulating these pathways during DC differentiation provides new strategies for generating potent DC vaccines for immunotherapy in patients with cancer
Oh et al., Exp Cell Res 2006 : Basal ERK phosphorylation was elevated and basal p38 kinase phosphorylation was reduced in paclitaxel non treated TB4-HeLa cells
Guest et al., Antioxid Redox Signal 2006 (Mechanotransduction, Cellular) : In conclusion, redox-sensitive activation of ERK1/2 ( MAPK ) and redox-insensitive activation of p38 ( MAPK ) regulate straininduced MCP-1 expression in RASM cells
Kook et al., Mol Cells 2008 (Mechanotransduction, Cellular) : Partial inhibition of p38 phosphorylation increased cellular levels of MyoD and p-ERK in stretched C2C12 cells, along with increased myotube formation ... These results suggest that cyclic stretch inhibits the myogenic differentiation of C2C12 cells by activating p38 mediated signaling and inhibiting ERK phosphorylation
Browne et al., Biochem Biophys Res Commun 2008 : ERK5 activation by either TGF-beta or epidermal growth factor (EGF) was also inhibited by the p38 MAP kinase inhibitor, SB-202190
Utsugi et al., J Immunol 2009 (MAP Kinase Signaling System) : PI3K p110beta siRNA inhibited JNK activation, but not p38 MAPK or ERK activation , stimulated by LPS, while PI3K p110alpha siRNA did not affect LPS induced JNK, p38 MAPK, or ERK activation in both cell types
Imai et al., J Periodontol 2009 (Halitosis...) : The activation of ERK1/2 and p38 induced by H2S was inhibited by the specific inhibitor of MAPK/ERK kinase ( [ MEK ] ; U0126 ) or p38 ( SB203580 )
Su et al., Anesth Analg 2012 (Disease Models, Animal...) : The response of the pial artery to hypotension and hypercapnia was monitored in piglets equipped with a closed cranial window before and after hypoxia and ischemia in the presence or absence of U0126, an inhibitor for the protein kinase upstream of ERK , sp600125, an inhibitor of c-Jun-N-terminal kinase or sb203580, an inhibitor of p38
Qi et al., Front Biosci (Elite Ed) 2012 (Reperfusion Injury) : Moreover, the phosphorylation of AKT and ERK1/2 in the liver was enhanced , while the phosphorylation of JNK, p38 and p65 was suppressed
Hu et al., J Biol Chem 2012 (Inflammation) : p38a deficiency also inhibits the activation of Akt but enhances the activation of ERK in response to T cell receptor engagement without impacting IL-2/Stat5 signaling
Gutstein et al., Anesthesiology 1997 : Transient experiments in COS cells revealed potent stimulation of ERK by mu and delta receptor activation, weak stimulation of stress activated protein kinase by all receptor types, and no activation of p38
Ludwig et al., J Biol Chem 1998 : ERK activation is strongly enhanced by overexpression of p38 and mitogen activated protein kinase kinase 6 ( MKK6 ) but is blocked by dominant negative kinase versions of p38 and MKK6 or the specific p38 inhibitor SB203580
Alexandrov et al., Mol Pharmacol 1998 : Anisomycin caused p38 activation and ERK inhibition quantitatively similar to those produced by phenylephrine
Ravanti et al., J Biol Chem 1999 : These results show that collagen dependent induction of MMP-13 in dermal fibroblasts requires p38 activity, and is inhibited by activation of ERK1,2