Park et al., J Biol Chem 2009
(Cysts...) :
In addition, we found that ERK activation was induced by PKD2 overexpression via B-Raf signaling, providing a possible molecular mechanism of cystogenesis
Tan et al., Arterioscler Thromb Vasc Biol 2009
:
Using multiple approaches, including dominant negative mutants and small interfering RNA knock-down, we found that lysoPC induced PKD2 activation was required for the activation of both ERK and p38 MAPK
Geng et al., Biochem Biophys Res Commun 2009
(Hypertrophy) :
In particular, PKD was critical for Ang II-induced ERK5 activation since silencing PKD by siRNA markedly inhibited Ang II-induced ERK5 activation